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Epratuzumab (Synonyms: Anti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41)

Catalog No. T76805 Copy Product Info
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Epratuzumab (AMG 41) is a humanized monoclonal antibody targeting CD22, also a tumor imaging agent that induces CD22 phosphorylation. It is used in autoimmune disease research.

Epratuzumab

Copy Product Info
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Catalog No. T76805
Synonyms Anti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41

Epratuzumab (AMG 41) is a humanized monoclonal antibody targeting CD22, also a tumor imaging agent that induces CD22 phosphorylation. It is used in autoimmune disease research.

Epratuzumab
Cas No. 205923-57-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$213In StockIn Stock
5 mg$558-In Stock
10 mg$893-In Stock
25 mg$1,320-In Stock
50 mg$1,780-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>95.0% (SDS-PAGE); 99.37% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Epratuzumab (AMG 41) is a humanized monoclonal antibody targeting CD22, also a tumor imaging agent that induces CD22 phosphorylation. It is used in autoimmune disease research.
In vitro
Epratuzumab binds to the CD22 extracellular domain with an affinity of K (D) = 0.7 nM.
Epratuzumab binds to B cell lines or primary B cells from patients with NHL, resulting in rapid internalization of the CD22/ antibody complex. [1]
SynonymsAnti-Human CD22 Recombinant Antibody, Antibody hLL 2, AMG41, AMG 41
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetSiglec-2/CD22
Chemical Properties
Molecular Weight146.58 kDa
Cas No.205923-57-5
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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