FLT3 Protein, Cynomolgus, Recombinant (hFc)

Catalog No. TMPK-00523 Copy Product Info

FLT3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.58 kDa and the accession number is A0A2K5VQ48.

FLT3 Protein, Cynomolgus, Recombinant (hFc)

Catalog No. TMPK-00523

Copy Product Info

FLT3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.58 kDa and the accession number is A0A2K5VQ48.

Pack Size	Price	USA Stock	Global Stock
5 μg	$58	7-10 days	7-10 days
10 μg	$92	7-10 days	7-10 days
20 μg	$148	7-10 days	7-10 days
50 μg	$289	7-10 days	7-10 days
100 μg	$487	7-10 days	7-10 days
200 μg	$883	7-10 days	7-10 days
500 μg	$1,950	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Information

Biological Activity	Immobilized Human FLT3 Ligand, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus FLT3, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA.
Description	FLT3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.58 kDa and the accession number is A0A2K5VQ48.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	A0A2K5VQ48
Synonyms	STK-1,FLT-3,FLK2,CD135
Construction	Gln28-Ser541
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	84.58 kDa (predicted). Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.