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IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

😃Good
Catalog No. T22856

IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.

IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

😃Good
Catalog No. T22856
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50InquiryInquiry
5 mg$143InquiryInquiry
10 mg$235InquiryInquiry
25 mg$329InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.
In vitro
Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia (Rijnierse, 2009)) and neutrophils (Braber and Thio (2012)), expanding their possible role as mediators in inflammatory disease.
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
Endotoxin< 1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Chemical Properties
Molecular Weight809.9
FormulaC37H59N7O13
SmilesC[C@@H](O)[C@H](N)C(NC(CC(O)=O)C(NC(CC1=CC=CC=C1)C(N[C@@H]([C@@H](O)C)C(NC(CC(C)C)C(N[C@H](C(N[C@H]([C@@H](C)CC)C(O)=O)=O)[C@@H](O)C)=O)=O)=O)=O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥81 mg/mL, Sonication is recommended.

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