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Livmoniplimab
😃Good
Catalog No. T77067Cas No. 2412004-88-5
Alias MHG-8, MHG8, ARGX-115, ARGX115, ABBV-151, ABBV151
Livmoniplimab (ABBV-151; ARGX-115) is a humanised monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, which blocks TGFβ1 release mediated by LRRC32, for the treatment of locally advanced or metastatic solid tumours.
Livmoniplimab
Livmoniplimab
😃Good
Catalog No. T77067Alias MHG-8, MHG8, ARGX-115, ARGX115, ABBV-151, ABBV151Cas No. 2412004-88-5
Livmoniplimab (ABBV-151; ARGX-115) is a humanised monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, which blocks TGFβ1 release mediated by LRRC32, for the treatment of locally advanced or metastatic solid tumours.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $257 | - | In Stock | |
| 5 mg | $668 | - | In Stock | |
| 10 mg | $1,070 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:≥95% (SDS-PAGE); 98.71% (SEC-HPLC)
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| Description | Livmoniplimab (ABBV-151; ARGX-115) is a humanised monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, which blocks TGFβ1 release mediated by LRRC32, for the treatment of locally advanced or metastatic solid tumours. |
| In vivo | Method: Seven-week-old female B-hGARP mice were subcutaneously inoculated with MC38 mouse colon cancer cells to establish tumor models. Livmoniplimab was administered at a dose of 250 μg via intraperitoneal injection three times a week for 3 weeks to evaluate its antitumor efficacy. Result: Livmoniplimab treatment Resulted in a 34.3% inhibition of tumor growth. [2] |
| Synonyms | MHG-8, MHG8, ARGX-115, ARGX115, ABBV-151, ABBV151 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TGFb1 |
| Molecular Weight | ~150 kDa |
| Cas No. | 2412004-88-5 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG4(S228P) kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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