IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)

Name: IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His)
Brand: TargetMol
SKU: TMPK-00654
Rating: 4.5 (1 reviews)

(Synonyms: IL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13) Copy Product Info

Synonyms: IL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13

Catalog No. TMPK-00654 Copy Product Info

IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 40.49 kDa and the accession number is G7NYP7.

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$92	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$289	7-10 days	7-10 days
100 µg	$487	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Cynomolgus IL-1R3, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
Description	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 40.49 kDa and the accession number is G7NYP7.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	G7NYP7
Construction	Ser21-Cys362
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	IL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13
Research Background	IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

Chemical Properties

Molecular Weight

40.49 kDa (predicted). Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) chemical structure | IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (aa 21-362, His) molecular weight