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Anti-CD200R Antibody-APC (9P451) is a APC-conjugated Rabbit antibody targeting CD200R. Anti-CD200R Antibody-APC (9P451) can be used in FCM.
Description | Anti-CD200R Antibody-APC (9P451) is a APC-conjugated Rabbit antibody targeting CD200R. Anti-CD200R Antibody-APC (9P451) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9P451 |
Reactivity | Mouse |
Verified Activity | Flow cytometric analysis of Mouse CD200R1 expression on BABL/c bone marrow cells. Cells were stained with APC-conjugated anti-Mouse CD200R1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD200R1 (rM CD200R1; TMPY-01665; NP_067300.1; Met1-Pro238) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors that is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | APC |
Others Formats | Unconjugated/PE |
Antibody Types Available | 3 |
Immunogen | Recombinant Mouse CD200R1 Protein (TMPY-01665) |
Antigen Species | Mouse |
Biology Area | Neuroinflammation, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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