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Anti-RBP4 Antibody (2J141)
😃Good
Catalog No. TMAY-00680
Alias retinol binding protein 4, plasma
Anti-RBP4 Antibody (2J141) is a Mouse antibody targeting RBP4. Anti-RBP4 Antibody (2J141) can be used in ELISA,IHC-P.
Anti-RBP4 Antibody (2J141)
Anti-RBP4 Antibody (2J141)
😃Good
Catalog No. TMAY-00680Alias retinol binding protein 4, plasma
Anti-RBP4 Antibody (2J141) is a Mouse antibody targeting RBP4. Anti-RBP4 Antibody (2J141) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-RBP4 Antibody (2J141) is a Mouse antibody targeting RBP4. Anti-RBP4 Antibody (2J141) can be used in ELISA,IHC-P. |
| Alias | retinol binding protein 4, plasma |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2J141 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human RBP4 in human pancreas with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human RBP4 in human liver with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. 3. Immunochemical staining of human RBP4 in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to proximal tubule. |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RBP4 (rh RBP4; TMPY-00907; NP_006735.2; Met 1-Leu 201). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
| Conjucates | Unconjugated |
| Others Formats | FITC/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human RBP4 protein (TMPY-00907) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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