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Anti-PODXL Antibody (7U177)
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Catalog No. TMAH-00994 Copy Product Info
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Anti-PODXL Antibody (7U177) is a Mouse antibody targeting PODXL. Anti-PODXL Antibody (7U177) can be used in ELISA,FCM,IF,IHC,IP,WB.
Anti-PODXL Antibody
(7U177)
(7U177)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-PODXL Antibody (7U177) is a Mouse antibody targeting PODXL. Anti-PODXL Antibody (7U177) can be used in ELISA,FCM,IF,IHC,IP,WB. |
| Ig Type | IgG2b |
| Clone | 7U177 |
| Reactivity | Human, Mouse, Rat |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Apical cell membrane. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus. Membrane raft. Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Glomerular epithelium cell (podocyte). |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Purity | >95% |
| Research Background | Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PODXL Protein |
| Antigen Species | Human |
| Gene Name | PODXL |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal Transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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