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Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody

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Catalog No. TMAC-02400

Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LIMK1/2 (Thr508/505). Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.

Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody

Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody

😃Good
Catalog No. TMAC-02400
Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LIMK1/2 (Thr508/505). Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LIMK1/2 (Thr508/505). Anti-Phospho-LIMK1/2 (Thr508/505) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:10000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundLIM domain kinase 1(LIMK1) Homo sapiens There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure. This protein also stimulates axon growth and may play a role in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cog
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human LIMK-1/2 around the phosphorylation site of Thr508/505
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 72 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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