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Anti-Nesprin 1 Antibody (1Z207)

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Catalog No. TMAC-02773

Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM.

Anti-Nesprin 1 Antibody (1Z207)

Anti-Nesprin 1 Antibody (1Z207)

😃Good
Catalog No. TMAC-02773
Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:200-1000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMulti-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nucleus-centrosome attachment and nuclear migration in neural progenitors implicating LINC complex association with SUN1/2 and probably association with cytoplasmic dynein-dynactin motor complexes; SYNE1 and SYNE2 may act redundantly. Required for centrosome migration to the apical cell surface during early ciliogenesis. May be involved in nuclear remodeling during sperm head formation in spermatogenenis; a probable SUN3:SYNE1/KASH1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized phosphopeptide: within Human Nesprin1 aa 8241-8290/8797
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 1011 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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