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Anti-Nesprin 1 Antibody (1Z207)
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Catalog No. TMAC-02773
Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM.
Anti-Nesprin 1 Antibody (1Z207)
Anti-Nesprin 1 Antibody (1Z207)
😃Good
Catalog No. TMAC-02773
Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Chemical Properties
| Description | Anti-Nesprin 1 Antibody (1Z207) is a Rabbit antibody targeting Nesprin 1. Anti-Nesprin 1 Antibody (1Z207) can be used in WB,ICC,IF,IHC,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:200-1000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nucleus-centrosome attachment and nuclear migration in neural progenitors implicating LINC complex association with SUN1/2 and probably association with cytoplasmic dynein-dynactin motor complexes; SYNE1 and SYNE2 may act redundantly. Required for centrosome migration to the apical cell surface during early ciliogenesis. May be involved in nuclear remodeling during sperm head formation in spermatogenenis; a probable SUN3:SYNE1/KASH1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized phosphopeptide: within Human Nesprin1 aa 8241-8290/8797 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 1011 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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