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Anti-DKK1 Antibody (4P933)

(Synonyms: SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1) Copy Product Info
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Synonyms: SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1

Catalog No. TMAH-00349 Copy Product Info
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Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
Anti-DKK1 Antibody (4P933)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
SynonymsSK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Ig Type
Human IgG1
Clone
4P933
Reactivity
Human
Application
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
Tissue SpecificityPlacenta.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundAntagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human DKK1 Protein
Antigen Species
Human
Gene Name
DKK1
Gene ID
Uniprot ID
Biology Area
Cardiovascular, Developmental biology, Immunology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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