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Anti-DKK1 Antibody (4P933)

😃Good
Catalog No. TMAH-00349
Alias SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1

Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.

Anti-DKK1 Antibody (4P933)

Anti-DKK1 Antibody (4P933)

😃Good
Catalog No. TMAH-00349Alias SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$349 7-10 days
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Instruction Manual of Detection Antibody
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Monoclonal

Application: ELISA

Reactivity: Human
AliasSK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Ig Type
Human IgG1
Clone
4P933
Reactivity
Human
Verified Activity
The Binding Activity of Human DKK1 with Anti-DKK1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DKK1 at 2 μg/mL can bind Anti-DKK1 recombinant antibody, the EC50 is 1.283-2.544 ng/mL.
Application
ELISA
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundAntagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human DKK1 Protein
Antigen Species
Human
Gene ID
22943
Uniprot ID
Biology Area
Cardiovascular, Developmental biology, Immunology, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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