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Anti-DKK1 Antibody (4P933)
😃Good
Catalog No. TMAH-00349
Alias SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
Anti-DKK1 Antibody (4P933)
Anti-DKK1 Antibody (4P933)
😃Good
Catalog No. TMAH-00349Alias SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DKK1 Antibody (4P933) is an antibody targeting DKK1. Anti-DKK1 Antibody (4P933) can be used in ELISA. |
| Synonyms | SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1 |
| Ig Type | Human IgG1 |
| Clone | 4P933 |
| Reactivity | Human |
| Verified Activity | The Binding Activity of Human DKK1 with Anti-DKK1 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DKK1 at 2 μg/mL can bind Anti-DKK1 recombinant antibody, the EC50 is 1.283-2.544 ng/mL. |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Placenta. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human DKK1 Protein |
| Antigen Species | Human |
| Gene Name | DKK1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cardiovascular, Developmental biology, Immunology, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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