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Piperonylic acid

Name: Piperonylic acid
Brand: TargetMol
SKU: TN6848
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN6848Cas No. 94-53-1

Alias 2H-1,3-benzodioxole-5-carboxylic acid

Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73A P450 subpopulation.

Piperonylic acid

🥰Excellent

Purity: 99.93%

Catalog No. TN6848Alias 2H-1,3-benzodioxole-5-carboxylic acidCas No. 94-53-1

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.93%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73A P450 subpopulation.
Synonyms	2H-1,3-benzodioxole-5-carboxylic acid

Chemical Properties

Molecular Weight	166.13
Formula	C₈H₆O₄
Cas No.	94-53-1
Smiles	OC(=O)C1=CC2=C(OCO2)C=C1
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (331.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0194 mL	30.0969 mL	60.1938 mL	300.9691 mL
5 mM	1.2039 mL	6.0194 mL	12.0388 mL	60.1938 mL
10 mM	0.6019 mL	3.0097 mL	6.0194 mL	30.0969 mL
20 mM	0.3010 mL	1.5048 mL	3.0097 mL	15.0485 mL
50 mM	0.1204 mL	0.6019 mL	1.2039 mL	6.0194 mL
100 mM	0.0602 mL	0.3010 mL	0.6019 mL	3.0097 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc