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2,4,6-Trimethylphenol

Name: 2,4,6-Trimethylphenol
Brand: TargetMol
SKU: T40607
Rating: 4.5 (1 reviews)

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Catalog No. T40607Cas No. 527-60-6

Alias Mesitol

2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.

2,4,6-Trimethylphenol

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Purity: 99.99%

Catalog No. T40607Alias MesitolCas No. 527-60-6

2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$31	7-10 days	7-10 days
5 g	$64	7-10 days	7-10 days
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.99%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.
In vitro	Peroxidatic substrates, namely catechol (CAT) and 2,4,6-trimethylphenol (TMP) were employed to investigate the chloride-responsive reactions facilitated by chloroperoxidase (CPO). TMP demonstrates consumption exclusively in the presence of chloride ions. While TMP acts as a competitive inhibitor in relation to CAT, the inhibition pattern shifts for CAT in the presence of TMP during chloride-dependent CPO-catalyzed peroxidation reactions. In direct competition studies, the TMP to CAT consumption ratio in the chloride-dependent CPO reaction exhibits an augmentation as the chloride concentration is elevated from 1.0 to 400 mM.[3]
Synonyms	Mesitol

Chemical Properties

Molecular Weight	136.19
Formula	C₉H₁₂O
Cas No.	527-60-6
Smiles	Cc1cc(C)c(O)c(C)c1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (440.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.69 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.3427 mL	36.7134 mL	73.4268 mL	367.1342 mL
5 mM	1.4685 mL	7.3427 mL	14.6854 mL	73.4268 mL
10 mM	0.7343 mL	3.6713 mL	7.3427 mL	36.7134 mL
20 mM	0.3671 mL	1.8357 mL	3.6713 mL	18.3567 mL
50 mM	0.1469 mL	0.7343 mL	1.4685 mL	7.3427 mL
100 mM	0.0734 mL	0.3671 mL	0.7343 mL	3.6713 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc