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2,4,6-Trimethylphenol

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Catalog No. T40607Cas No. 527-60-6
Alias Mesitol

2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.

2,4,6-Trimethylphenol

2,4,6-Trimethylphenol

🥰Excellent
Purity: 99.84%
Catalog No. T40607Alias MesitolCas No. 527-60-6
2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$31-In Stock
5 g$64-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.84%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.
In vitro
Peroxidatic substrates, namely catechol (CAT) and 2,4,6-trimethylphenol (TMP) were employed to investigate the chloride-responsive reactions facilitated by chloroperoxidase (CPO). TMP demonstrates consumption exclusively in the presence of chloride ions. While TMP acts as a competitive inhibitor in relation to CAT, the inhibition pattern shifts for CAT in the presence of TMP during chloride-dependent CPO-catalyzed peroxidation reactions. In direct competition studies, the TMP to CAT consumption ratio in the chloride-dependent CPO reaction exhibits an augmentation as the chloride concentration is elevated from 1.0 to 400 mM.[3]
SynonymsMesitol
Chemical Properties
Molecular Weight136.19
FormulaC9H12O
Cas No.527-60-6
SmilesCc1cc(C)c(O)c(C)c1
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (440.56 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (14.69 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.3427 mL36.7134 mL73.4268 mL367.1342 mL
5 mM1.4685 mL7.3427 mL14.6854 mL73.4268 mL
10 mM0.7343 mL3.6713 mL7.3427 mL36.7134 mL
20 mM0.3671 mL1.8357 mL3.6713 mL18.3567 mL
50 mM0.1469 mL0.7343 mL1.4685 mL7.3427 mL
100 mM0.0734 mL0.3671 mL0.7343 mL3.6713 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2,4,6-Trimethylphenol
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