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13(S)-HpODE

Name: 13(S)-HpODE
Brand: TargetMol
SKU: T37393
Rating: 4.5 (1 reviews)

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Catalog No. T37393Cas No. 33964-75-9

13(S)-HpODE, a metabolite present in potato and Homo sapiens, is the (S)-enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13(S)HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13(S)HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis.

13(S)-HpODE

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Catalog No. T37393Cas No. 33964-75-9

Pack Size	Price	USA Warehouse	Global Warehouse
50 μg	$236	35 days	35 days
100 μg	$429	35 days	35 days
500 μg	$1,980	35 days	35 days
1 mg	$3,420	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description

In vivo

Methods: Wild-type C57BL/6J mice were injected subcutaneously in the back with 200 μL of vehicle containing 0, 0.75, 1.5, 3, and 6 μg of 13(S)-HpODE per mouse.
Results: 13(S)-HpODE administration dose-dependently reduced the anti-inflammatory properties of HDL in mice. [4]

Chemical Properties

Molecular Weight	312.44
Formula	C₁₈H₃₂O₄
Cas No.	33964-75-9
Smiles	[C@@H](/C=C/C=C\CCCCCCCC(O)=O)(CCCCC)OO

Storage & Solubility Information

Storage

store at low temperature | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (3.2 mM), Sonication is recommended.

DMSO: 10 mg/mL (32.01 mM), Sonication is recommended.

Ethanol: 10 mg/mL (32.01 mM), Sonication is recommended.

DMF: 10 mg/mL (32.01 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	3.2006 mL	16.0031 mL	32.0061 mL	160.0307 mL

DMSO/Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6401 mL	3.2006 mL	6.4012 mL	32.0061 mL
10 mM	0.3201 mL	1.6003 mL	3.2006 mL	16.0031 mL
20 mM	0.1600 mL	0.8002 mL	1.6003 mL	8.0015 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc