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Anti-CD93/C1qR1 Antibody-PE (8N985)
🥰Excellent
Catalog No. TMAY-02387P
Anti-CD93/C1qR1 Antibody-PE (8N985) is a PE-conjugated Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody-PE (8N985) can be used in FCM.
Anti-CD93/C1qR1 Antibody-PE (8N985)
Anti-CD93/C1qR1 Antibody-PE (8N985)
🥰Excellent
Catalog No. TMAY-02387P
Anti-CD93/C1qR1 Antibody-PE (8N985) is a PE-conjugated Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody-PE (8N985) can be used in FCM.
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD93/C1qR1 Antibody-PE (8N985) is a PE-conjugated Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody-PE (8N985) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 8N985 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD93 expression on human whole blood monocytes. Cells were stained with PE-conjugated anti-Human CD93. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93 / C1qR (rh CD93 / C1qR; TMPY-02268; Q9NPY3; Met1-Lys580) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD93 / C1qR Protein (TMPY-02268) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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