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Thrombopoietin Protein, Human, Recombinant (His)
(Synonyms: Thrombopoietin, THPO, Myeloproliferative leukemia virus oncogene ligand, Megakaryocyte growth and development factor, Megakaryocyte colony-stimulating factor, C-mpl ligand) Copy Product InfoSynonyms: Thrombopoietin, THPO, Myeloproliferative leukemia virus oncogene ligand, Megakaryocyte growth and development factor, Megakaryocyte colony-stimulating factor, C-mpl ligand
Catalog No. TMPJ-00235 Copy Product Info
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $74 | - | In Stock | |
| 10 μg | $118 | In Stock | In Stock | |
| 20 μg | $190 | 7-10 days | 7-10 days | |
| 50 μg | $350 | 7-10 days | 7-10 days | |
| 100 μg | $513 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95 % as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N, C-6xHis |
| Accession Number | P40225 |
| Amino Acid | Ser22-Gly353 |
| Construction | Ser22-Gly353 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) https://cdn.targetmol.com/group3/M00/13/6C/CgoaEWZG00KEKL8EAAAAACLFa5E556.png |
| Endotoxin | < 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 150 mM NaCl, pH 8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Thrombopoietin, THPO, Myeloproliferative leukemia virus oncogene ligand, Megakaryocyte growth and development factor, Megakaryocyte colony-stimulating factor, C-mpl ligand |
| Research Background |
| Molecular Weight | 70-90 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Thrombopoietin Protein, Human, Recombinant (His) chemical structure | Thrombopoietin Protein, Human, Recombinant (His) molecular weight
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