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GDP-D-mannose disodium

Name: GDP-D-mannose disodium
Brand: TargetMol
SKU: T65209
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T65209 Copy Product Info

Purity: 99.96%

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GDP-D-mannose disodium consists of GDP-α-D-mannose and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and a precursor for GDP-β-L-fucose biosynthesis. It competitively inhibits GTP with a Ki of 14.7 μM and non-competitively inhibits mannose-1-P with a Ki of 115 μM.

GDP-D-mannose disodium

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Catalog No. T65209

Cas No. 103301-73-1

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Pack Size	Price	USA Stock	Global Stock
1 mg	$34	-	In Stock
5 mg	$77	-	In Stock
10 mg	$123	-	In Stock
25 mg	$198	-	In Stock
50 mg	$297	-	In Stock
100 mg	$453	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.96%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	649.31
Formula	C₁₆H₂₃N₅Na₂O₁₆P₂
Cas No.	103301-73-1
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OC2O[C@@H]([C@H]([C@@H]([C@@H]2O)O)O)CO)([O-])=O)([O-])=O)N3C4=C(C(N=C(N4)N)=O)N=C3.[Na+].[Na+]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 9.41 mg/mL (14.49 mM), Sonication is recommended.

H2O: 80.00 mg/mL (123.21 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.5401 mL	7.7005 mL	15.4010 mL	77.0048 mL
5 mM	0.3080 mL	1.5401 mL	3.0802 mL	15.4010 mL
10 mM	0.1540 mL	0.7700 mL	1.5401 mL	7.7005 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.0770 mL	0.3850 mL	0.7700 mL	3.8502 mL
50 mM	0.0308 mL	0.1540 mL	0.3080 mL	1.5401 mL
100 mM	0.0154 mL	0.0770 mL	0.1540 mL	0.7700 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc