Powder: -20°C for 3 years | In solvent: -80°C for 1 year
17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 μg | 35 days | $ 223.00 | |
100 μg | 35 days | $ 420.00 |
Description | 17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases in the spontaneous beating of NRCMs.3,4 |
Molecular Weight | 318.457 |
Formula | C20H30O3 |
CAS No. | 725246-18-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
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17R(18S)-EpETE 725246-18-4 17R(18S) EpETE 17REpETE 17R(18S)EpETE inhibitor inhibit