Anti-Galectin-3/LGALS3 Polyclonal Antibody

Name: Anti-Galectin-3/LGALS3 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00735
Rating: 4.5 (1 reviews)

(Synonyms: MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3) Copy Product Info

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Synonyms: MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3

Catalog No. TMAB-00735 Copy Product Info

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Anti-Galectin-3/LGALS3 Polyclonal Antibody is a Rabbit antibody targeting Galectin-3/LGALS3. Anti-Galectin-3/LGALS3 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.

Anti-Galectin-3/LGALS3 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$220	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$527	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Galectin-3/LGALS3 Polyclonal Antibody is a Rabbit antibody targeting Galectin-3/LGALS3. Anti-Galectin-3/LGALS3 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Synonyms	MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3
Ig Type	IgG
Reactivity	Human,Mouse (predicted:Rat,Dog)

Application	FCM IF IHC-Fr IHC-P WB
Recommended Dose	WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
Tissue Specificity	A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene encodes a member of thegalectinfamily of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human Galectin 3
Antigen Species	Human
Gene Name	LGALS3
Gene ID	3958
Protein Name	Galectin-3
Uniprot ID	P17931
Biology Area	Nuclear Proteins,Cell differentiation
Function	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.