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Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $69 | 7-10 days | 7-10 days |
| Description | Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes. |
| In vivo | Intact, cycling female mice received subcutaneous injections of Antipain dihydrochloride (3 mg) for 16 days, resulting in significant diminution in uterine weight and total DNA compared to untreated controls[1].Antipain dihydrochloride (100 μg/g body weight; i.p.; at 12-hour intervals from 0 to 120 h or 240 to 360 h) exhibits an inhibitory effect on urethane-induced lung neoplasia in mice[2]. |
| Synonyms | BDBM-32804, BDBM32804, BDBM 32804, Antipain, Antipain 2HCl |
| Molecular Weight | 677.62 |
| Formula | C27H46Cl2N10O6 |
| Cas No. | 37682-72-7 |
| Smiles | O=CC(CCCNC(N)=N)NC(C(C(C)C)NC(C(CCCNC(N)=N)NC(NC(CC1=CC=CC=C1)C(O)=O)=O)=O)=O.Cl.Cl |
| Relative Density. | 1.2423 g/cm3 (Estimated) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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