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Anti-GDF-15 Antibody (9A125)
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Catalog No. TMAY-01352
Alias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Anti-GDF-15 Antibody (9A125) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9A125) can be used in IHC-P.
Anti-GDF-15 Antibody (9A125)
Anti-GDF-15 Antibody (9A125)
😃Good
Catalog No. TMAY-01352Alias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Anti-GDF-15 Antibody (9A125) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9A125) can be used in IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-GDF-15 Antibody (9A125) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (9A125) can be used in IHC-P. |
| Synonyms | PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15 |
| Ig Type | Mouse IgG1 |
| Clone | 9A125 |
| Reactivity | Human |
| Specificity | Human GDF-15 |
| Verified Activity | 1. Immunochemical staining of human GDF15 in human prostate with mouse monoclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human GDF15 in human placenta with mouse monoclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Application | |
| Recommended Dose | IHC-P: 1:30-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GDF15 (rh GDF15; TMPY-04727; NP_004855.2; Ala197-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human GDF15 Protein (TMPY-04727) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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