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Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody (Synonyms: p-IKK- alpha/IKBKB (Ser176/177), p-IKK- al...)
Catalog No. TMAC-02126 Copy Product Info
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Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKBKA/IKBKB (Ser176/177). Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody can be used in WB,IHC,IF,ELISA.
Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-02126
Synonyms p-IKK- alpha/IKBKB (Ser176/177), p-IKK- alpha/IKBKB (S176/177), IKK- alpha/IKBKB (p-Ser176/177), IKK- alpha/IKBKB (p-S176/177)
Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKBKA/IKBKB (Ser176/177). Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody can be used in WB,IHC,IF,ELISA.
Anti-Phospho-IKBKA/IKBKB
(Ser176/177) Polyclonal Antibody
(Ser176/177) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IKBKA/IKBKB (Ser176/177). Anti-Phospho-IKBKA/IKBKB (Ser176/177) Polyclonal Antibody can be used in WB,IHC,IF,ELISA. |
| Synonyms | p-IKK- alpha/IKBKB (Ser176/177), p-IKK- alpha/IKBKB (S176/177), IKK- alpha/IKBKB (p-Ser176/177), IKK- alpha/IKBKB (p-S176/177) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. All Lanes: IKK-alpha/ beta (Phospho-Ser176/177) Antibody at 1/ 500 dilution. Lane1: Jurkat treated with 20ng/ml TNF-α for 30min Cell lysate, Lane2: Huvec treated with 100ng/ml EGF for 30min Cell lysate, Lane3: Hela treated with 100ng/ml EGF for 30min Cell lysate, Lane4: HepG2 treated with 100ng/ml EGF for 30min Cell lysate, Lane5: Mouse Brain Tissue lysate, Lane6:Mouse lung Tissue lysate, Lane7: Rat Liver Tissue lysateLysates/proteins at 40 μg per lane. Secondary: Goat Anti-Rabbit IgG (HRP) at 1/20000 dilution, Predicted band size: 85kDa, Observed band size: 80kDa.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 176/177 (Q-G-S(p)-L-C) derived from Human IKK-alpha/beta |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 85 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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