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Anti-IL-4 Polyclonal Antibody
😃Good
Catalog No. TMAB-00961
Alias interleukin 4, BSF-1
Anti-IL-4 Polyclonal Antibody is a Rabbit antibody targeting IL-4. Anti-IL-4 Polyclonal Antibody can be used in WB.
Anti-IL-4 Polyclonal Antibody
Anti-IL-4 Polyclonal Antibody
😃Good
Catalog No. TMAB-00961Alias interleukin 4, BSF-1
Anti-IL-4 Polyclonal Antibody is a Rabbit antibody targeting IL-4. Anti-IL-4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL-4 Polyclonal Antibody is a Rabbit antibody targeting IL-4. Anti-IL-4 Polyclonal Antibody can be used in WB. |
| Synonyms | interleukin 4, BSF-1 |
| Ig Type | IgG |
| Reactivity | Mouse |
| Verified Activity | Sample: Lane 1: Recombinant mouse IL-4 protein, His (HEK293) Primary: Anti-IL4 (TMAB-00961) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: mouse IL-4 |
| Antigen Species | Mouse |
| Gene Name | IL4 |
| Gene ID | |
| Protein Name | Interleukin-4 |
| Uniprot ID | |
| Biology Area | Interleukins,Regulatory T Cells,Interleukins |
| Function | Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. |
| Molecular Weight | Theoretical: 14 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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