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tPA Protein, Mouse, Recombinant (His)

(Synonyms: t-PA, tPA, Reteplase, PLAT, Alteplase) Copy Product Info

Synonyms: t-PA, tPA, Reteplase, PLAT, Alteplase

Catalog No. TMPK-00810 Copy Product Info
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the
predominant route for enhancing cell survival is via an mTORdependent mechanism.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$56-In Stock
10 μg$88-In Stock
20 μg$143-In Stock
50 μg$278-In Stock
100 μg$465In StockIn Stock
200 μg$8397-10 days7-10 days
500 μg$1,8507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the
predominant route for enhancing cell survival is via an mTORdependent mechanism.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberP11214
ConstructionSer33-Gln559, which consists of two chains: chain A (Ser33-Arg308) and chain B (Ile309-Gln559)
Protein Purity
> 95% as determined by Tris-Bis PAGE
https://cdn.targetmol.com/group3/M00/3E/E2/CgoaEGbGogmEffOLAAAAAGxpt4k243.png
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymst-PA, tPA, Reteplase, PLAT, Alteplase
Research Background
Chemical Properties
Molecular Weight60.57 kDa (predicted). It migrates to 13-15 kDa (chain A and chain B fragment), 30-34 kDa and 35-40 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: tPA Protein, Mouse, Recombinant (His) chemical structure | tPA Protein, Mouse, Recombinant (His) molecular weight