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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

2,2,5,7,8-Pentamethyl-6-Chromanol

🥰Excellent
Catalog No. T14008Cas No. 950-99-2
Alias PMC

2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the antioxidant component of vitamin E (α-tocopherol) and exhibits significant androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.

2,2,5,7,8-Pentamethyl-6-Chromanol

2,2,5,7,8-Pentamethyl-6-Chromanol

🥰Excellent
Purity: 98.72%
Catalog No. T14008Alias PMCCas No. 950-99-2
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the antioxidant component of vitamin E (α-tocopherol) and exhibits significant androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
Pack SizePriceAvailabilityQuantity
500 mg$53In Stock
1 g$77In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:98.72%
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COA LCMS HPLC HNMR

Product Introduction

Bioactivity
Description
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the antioxidant component of vitamin E (α-tocopherol) and exhibits significant androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.
SynonymsPMC
Chemical Properties
Molecular Weight220.31
FormulaC14H20O2
Cas No.950-99-2
SmilesCc1c(C)c2OC(C)(C)CCc2c(C)c1O
Relative Density.1.034 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (1134.76 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.5391 mL22.6953 mL45.3906 mL226.9529 mL
5 mM0.9078 mL4.5391 mL9.0781 mL45.3906 mL
10 mM0.4539 mL2.2695 mL4.5391 mL22.6953 mL
20 mM0.2270 mL1.1348 mL2.2695 mL11.3476 mL
50 mM0.0908 mL0.4539 mL0.9078 mL4.5391 mL
100 mM0.0454 mL0.2270 mL0.4539 mL2.2695 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

InhibitorinhibitAndrogenReceptorAndrogen Receptor2,2,5,7,8-Pentamethyl-6-Chromanol2,2,5,7,8Pentamethyl6Chromanol2,2,5,7,8 Pentamethyl 6 Chromanol
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