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CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His)
(Synonyms: IDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5) Copy Product InfoSynonyms: IDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5
Catalog No. TMPY-07105 Copy Product Info
CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) is expressed in HEK293 Cells. The accession number is P51685.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $1,260 | 7-10 days | 7-10 days | |
| 20 µg | $2,150 | 7-10 days | 7-10 days | |
| 50 µg | $4,390 | 7-10 days | 7-10 days | |
| 100 µg | $7,560 | 7-10 days | 7-10 days | |
| 200 µg | $9,870 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) (Cat#TMPY-07105) at 5 μg/mL (100 μL/well) can bind Leronlimab-Derived Anti-CCR5 Antibody, Human IgG1, the EC50 is 10-32 ng/mL. |
| Description | CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) is expressed in HEK293 Cells. The accession number is P51685. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-Flag-Strep, C-His |
| Accession Number | P51685 |
| Construction | A DNA sequence encoding the Human CCR5 (P51685)(Met1-Arg223) & (Glu227-Arg319) was expressed and linked by a Fusion Protein, with a Flag and a polyhistidine tag at the N-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our Nanodisc platform. Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment. |
| Protein Purity | ≥ 90% as determined by SDS-PAGE. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as sterile 50 mM HEPES, 150 mM NaCl, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Synonyms | IDDM22, CMKBR5, CKR-5, CKR5, CD195, CCR-5, CC-CKR-5, CCCKR5 |
| Molecular Weight | 43.96 kDa (predicted); 42.1 kDa (reducing contition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
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Related Tags: CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) chemical structure | CCR5 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) molecular weight
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