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Anti-Caspase 5 Antibody (3R203) (Synonyms: TY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease|...)

Catalog No. TMAC-00571 Copy Product Info
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Anti-Caspase 5 Antibody (3R203) is a Rabbit antibody targeting Caspase 5. Anti-Caspase 5 Antibody (3R203) can be used in ICC/IF,IHC,IP,WB.

Anti-Caspase 5 Antibody (3R203)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00571
Synonyms TY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease, ICH 3, ICERELIII, ICEREL III, ICE(rel)III, ICE(rel) III, ICE, Caspase-5 subunit p20, Caspase-5, Caspase5, caspase 5 apoptosis related cysteine protease, Caspase 5 apoptosis related cysteine peptidase, CASP5, CASP 5, Apoptosis related cysteine protease

Anti-Caspase 5 Antibody (3R203) is a Rabbit antibody targeting Caspase 5. Anti-Caspase 5 Antibody (3R203) can be used in ICC/IF,IHC,IP,WB.

Anti-Caspase 5 Antibody
(3R203)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Caspase 5 Antibody (3R203) is a Rabbit antibody targeting Caspase 5. Anti-Caspase 5 Antibody (3R203) can be used in ICC/IF,IHC,IP,WB.
SynonymsTY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease, ICH 3, ICERELIII, ICEREL III, ICE(rel)III, ICE(rel) III, ICE, Caspase-5 subunit p20, Caspase-5, Caspase5, caspase 5 apoptosis related cysteine protease, Caspase 5 apoptosis related cysteine peptidase, CASP5, CASP 5, Apoptosis related cysteine protease
Ig Type
IgG
Clone
3R203
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Caspase 5 antibody. Counter stained with hematoxylin.
2. ICC staining Caspase 5 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Caspase 5 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Caspase 5 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCaspases are cysteine proteases which play important roles in the activation of cytokines and in apoptosis. The ICE subfamily of caspases comprises peptides closely related to caspase-1, which promotes maturation of interleukin 1β (IL-1β) and interleukin-18 (IL-18) by proteolytic cleavage of precursor forms to generate biologically active peptides. Both caspase-4 and caspase-5 are members of the caspase-1 subfamily, and are more closely related to each other than to other homologues. Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating the caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. The human caspase 5 gene maps to chromosome 11q22.2-q22.3 and encodes a protein whose expression is barely detectable in most tissues except brain, with highest expression levels being found in lung, liver and skeletal muscle.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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