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GDF-11 Protein, Human, Recombinant
(Synonyms: Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11) Copy Product InfoSynonyms: Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11
Catalog No. TMPJ-00713 Copy Product Info
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | - | In Stock | |
| 10 μg | $183 | - | In Stock | |
| 20 μg | $292 | - | In Stock | |
| 50 μg | $545 | - | In Stock | |
| 100 μg | $792 | - | In Stock | |
| 200 μg | $1,150 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,970 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:SDS-PAGE: 98%; SEC-HPLC: 97%
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| Description | Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | O95390 |
| Amino Acid | Asn299-Ser407 |
| Construction | Asn299-Ser407 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) https://cdn.targetmol.com/group3/M00/13/65/CgoaEWZG0ymEWl-AAAAAAPu15Dg751.png |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50% glycerol, pH 7.4. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11 |
| Research Background |
| Molecular Weight | 13-20 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: GDF-11 Protein, Human, Recombinant chemical structure | GDF-11 Protein, Human, Recombinant molecular weight
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