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Anti-Phospho-AS160 (Ser318) Polyclonal Antibody

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Catalog No. TMAC-00280

Anti-Phospho-AS160 (Ser318) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AS160 (Ser318). Anti-Phospho-AS160 (Ser318) Polyclonal Antibody can be used in WB.

Anti-Phospho-AS160 (Ser318) Polyclonal Antibody

Anti-Phospho-AS160 (Ser318) Polyclonal Antibody

😃Good
Catalog No. TMAC-00280
Anti-Phospho-AS160 (Ser318) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AS160 (Ser318). Anti-Phospho-AS160 (Ser318) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-AS160 (Ser318) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AS160 (Ser318). Anti-Phospho-AS160 (Ser318) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundTBC1 domain family member 4(TBC1D4) Homo sapiens This gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2), a calmodulin-binding domain (CBD), a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4), important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insulin, this protein is phosphorylated, dissociates from GLUT4 vesicles, resulting in increased GLUT4 at the cell surface, and enhanced glucose transport. Ph
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human AS160 around the phosphorylation site of Ser318
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 145 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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