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LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: LRRC15, LIB, Leucine-rich repeat-containing protein 15, Leucine-rich repeat protein induced by β-amyloid homolog, Leucine-rich repeat protein induced by beta-amyloid homolog) Copy Product InfoSynonyms: LRRC15, LIB, Leucine-rich repeat-containing protein 15, Leucine-rich repeat protein induced by β-amyloid homolog, Leucine-rich repeat protein induced by beta-amyloid homolog
Catalog No. TMPJ-00338 Copy Product Info
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal tissue. Remarkably, LRRC15 was relatively abundant in mineralized tissues. That LRRC15 was significantly induced after osteogenic differentiation, while in the MSCs from bone marrow of ovariectomized mice the expression of LRRC15 was remarkably decreased and LRRC15 regulated osteogenic differentiation in a p65-dependent manner.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $129 | - | In Stock | |
| 10 µg | $213 | - | In Stock | |
| 20 µg | $355 | 7-10 days | 7-10 days | |
| 50 µg | $625 | 7-10 days | 7-10 days | |
| 100 µg | $963 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal tissue. Remarkably, LRRC15 was relatively abundant in mineralized tissues. That LRRC15 was significantly induced after osteogenic differentiation, while in the MSCs from bone marrow of ovariectomized mice the expression of LRRC15 was remarkably decreased and LRRC15 regulated osteogenic differentiation in a p65-dependent manner. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis-Avi |
| Accession Number | Q8TF66 |
| Amino Acid | Tyr22-Gly538 |
| Construction | Tyr22-Gly538 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | LRRC15, LIB, Leucine-rich repeat-containing protein 15, Leucine-rich repeat protein induced by β-amyloid homolog, Leucine-rich repeat protein induced by beta-amyloid homolog |
| Research Background | The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal tissue. Remarkably, LRRC15 was relatively abundant in mineralized tissues. That LRRC15 was significantly induced after osteogenic differentiation, while in the MSCs from bone marrow of ovariectomized mice the expression of LRRC15 was remarkably decreased and LRRC15 regulated osteogenic differentiation in a p65-dependent manner. |
| Molecular Weight | 60-85 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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