3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 814.00 | |
500 μg | 5 days | $ 3,250.00 | |
1 mg | 5 days | $ 5,440.00 |
Description | 3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. |
Species | SARS-CoV-2 |
Expression System | E. coli |
Tag | No Tag |
Accession Number | YP_009725301.1 |
Synonyms | 3CL Protease, 3CL-Mpro, Mpro, M Proteinase |
Construction | Recombinant SARS-CoV-2 3CLpro/3C-like Protease Protein (P132H) is expressed from E.coli without tag. It contains Ser1-Gln306(P132H).[Accession |YP_009725301.1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | The protein has a predicted MW of 33.8 kDa same as Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in 25mM HEPES, 2.5mM DTT, 10% Glycerol (pH 7.5). |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | 3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant 3CL Protease 3CL-Mpro Mpro M Proteinase recombinant recombinant-proteins proteins protein