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Synonyms: microtubule-associated protein 1 light chain 3 α, microtubule-associated protein 1 light chain 3 alpha, MAP1BLC3, MAP1ALC3, LC3A, LC3, ATG8E


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µg | $38 | - | In Stock | |
| 100 µg | $58 | - | In Stock | |
| 200 µg | $93 | 7-10 days | 7-10 days | |
| 500 µg | $172 | - | In Stock | |
| 1 mg | $343 | 7-10 days | 7-10 days |
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver, and skeletal muscle but are absent in thymus and peripheral blood leukocytes. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His |
| Accession Number | Q9H492-1 |
| Construction | A DNA sequence encoding the mature form of human MAP1LC3A (Q9H492-1) (Met1-Phe121) was expressed with a polyhistide tag at the C-terminus. Predicted N terminal: Met |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 10% glycerol, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 2.5 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | microtubule-associated protein 1 light chain 3 α, microtubule-associated protein 1 light chain 3 alpha, MAP1BLC3, MAP1ALC3, LC3A, LC3, ATG8E |
| Research Background | LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver, and skeletal muscle but are absent in thymus and peripheral blood leukocytes. |
| Molecular Weight | 15.1 kDa (predicted); 17 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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