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Anti-AHR Polyclonal Antibody 2
(Synonyms: Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor) Copy Product Info
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Synonyms: Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor
Catalog No. TMAB-00081 Copy Product Info
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Anti-AHR Polyclonal Antibody 2 is a Rabbit antibody targeting AHR. Anti-AHR Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P,WB.
Anti-AHR Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:1mg/ml
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-AHR Polyclonal Antibody 2 is a Rabbit antibody targeting AHR. Anti-AHR Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Class E basic helix-loop-helix protein 76 (bHLHe76), bHLHe76, Aryl hydrocarbon receptor, AHR, Ah receptor |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. |
| Tissue Specificity | Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. |
| Immunogen | KLH conjugated synthetic peptide: human AHR |
| Antigen Species | Human |
| Gene Name | AHR |
| Gene ID | |
| Protein Name | Aryl hydrocarbon receptor |
| Uniprot ID | |
| Function | Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. |
| Molecular Weight | Theoretical: 93 kDa. Actual: 120 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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