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Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

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Catalog No. TN6600Cas No. 56317-05-6

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

🥰Excellent
Purity: 99.47%
Catalog No. TN6600Cas No. 56317-05-6
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
Pack SizePriceAvailabilityQuantity
1 mg$112In Stock
5 mg$288In Stock
10 mg$525In Stock
25 mg$846In Stock
50 mgPreferentialIn Stock
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Purity:99.47%
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Product Introduction

Bioactivity
Description
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
Targets&IC50
α-glucosidase:5.60 ± 1.57 μM, HIV-2:5.19 μM
In vitro
Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 3; KGG) (12、25、50 μM) inhibited the expression of NLRP3 protein in RAW 264.7 cells. Treatment with the isolated compounds 3 significantly inhibited IL-1β protein expression in RAW 264.7 cells in a concentration-dependent manner.[2]
Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 1) showed most potent inhibition at the IC50 value of 0.46 mM. The enzyme steady-state kinetic study revealed that 1 exerted competitiv inhibition with respect to ATP.[3]
Chemical Properties
Molecular Weight600.48
FormulaC28H24O15
Cas No.56317-05-6
SmilesO(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(O)C=C3)[C@@H]4O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.87 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

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