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Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

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Catalog No. TN6600Cas No. 56317-05-6

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside

🥰Excellent
Purity: 99.91%
Catalog No. TN6600Cas No. 56317-05-6
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$112In StockIn Stock
5 mg$288In StockIn Stock
10 mg$525-In Stock
25 mg$846-In Stock
50 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.91%
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COA LCMS

Product Introduction

Bioactivity
Description
Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.
Targets&IC50
α-glucosidase:5.60 ± 1.57 μM, HIV-2:5.19 μM
In vitro
Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 3; KGG) (12、25、50 μM) inhibited the expression of NLRP3 protein in RAW 264.7 cells. Treatment with the isolated compounds 3 significantly inhibited IL-1β protein expression in RAW 264.7 cells in a concentration-dependent manner.[2]
Kaempferol 3-O-(6″- galloyl)-β-D-glucopyranoside (compounds 1) showed most potent inhibition at the IC50 value of 0.46 mM. The enzyme steady-state kinetic study revealed that 1 exerted competitiv inhibition with respect to ATP.[3]
Chemical Properties
Molecular Weight600.48
FormulaC28H24O15
Cas No.56317-05-6
SmilesO(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(O)C=C3)[C@@H]4O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.87 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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