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APBA3 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00722
Synonyms: Neuronal Munc18-1-Interacting Protein 3, Neuron-Specific X11L2 Protein, Amyloid Beta A4 Precursor Protein-Binding Family A Member 3, Adapter protein X11γ, Mint-3, Adapter protein X11Gamma, Amyloid β A4 Precursor Protein-Binding Family A Member 3, MINT3, APBA3, X11L2

Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.

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APBA3 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.
Species Human
Expression System E. coli
Tag C-6His
Accession Number O96018
Synonyms Neuronal Munc18-1-Interacting Protein 3, Neuron-Specific X11L2 Protein, Amyloid Beta A4 Precursor Protein-Binding Family A Member 3, Adapter protein X11γ, Mint-3, Adapter protein X11Gamma, Amyloid β A4 Precursor Protein-Binding Family A Member 3, MINT3, APBA3, X11L2
Amino Acid Met1-Leu138
Construction Recombinant Human Amyloid Beta A4 Precursor Protein-Binding Family A Member 3 is produced by our E.coli expression system and the target gene encoding Met1-Leu138 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 20 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.

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Keywords

APBA3 Protein, Human, Recombinant (His) MINT 3 APBA 3 APBA-3 Neuronal Munc18-1-Interacting Protein 3 Neuron-Specific X11L2 Protein Amyloid Beta A4 Precursor Protein-Binding Family A Member 3 Adapter protein X11γ Mint-3 Adapter protein X11Gamma Amyloid β A4 Precursor Protein-Binding Family A Member 3 MINT3 APBA3 X11L2 recombinant recombinant-proteins proteins protein

 

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