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LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep)

(Synonyms: HG38, GRP49, GPR67, GPR49, FEX) Copy Product Info

Synonyms: HG38, GRP49, GPR67, GPR49, FEX

Catalog No. TMPY-07172 Copy Product Info
LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O75473.
LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep)
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Pack SizePriceUSA StockGlobal StockQuantity
10 µg$4607-10 days7-10 days
20 µg$7737-10 days7-10 days
50 µg$1,1807-10 days7-10 days
100 µg$1,8707-10 days7-10 days
200 µg$2,8007-10 days7-10 days
500 µg$6,6307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07172) at 5 μg/mL (100 μL/well) can bind Petosemtamab Derived Anti-CCR5 Monoclonal antibody, Human IgG1, the EC50 is 1.5-5 ng/mL.
Description
LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is O75473.
Species
Human
Expression System
HEK293 Cells
TagN-Flag, C-His-Strep
Accession NumberO75473
ConstructionA DNA sequence encoding the Human LGR5 -VLP (O75473) (Gly22-Ser844) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
SynonymsHG38, GRP49, GPR67, GPR49, FEX
Research Background
Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) plays a vital role in the development of malignant tumors. Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) is highly expressed in colorectal tumors and marks colon cancer stem cells that drive tumor growth and metastasis. LGR5, a well-characterized marker of stem cell and cancer stem cells (CSCs), is best known as a transmembrane receptor for increases canonical Wnt signaling amplitude. LGR5 expressing cells are not limited to the postulated stem cell niche but LGR5 expression is hormonally regulated.
Chemical Properties
Molecular Weight95.01 kDa (predicted)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageSamples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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Related Tags: LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) chemical structure | LGR-5 Protein-VLP, Human, Recombinant (Flag & His-Strep) molecular weight