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TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $86 | 7-10 days | |
| 10 μg | $140 | 7-10 days | |
| 20 μg | $223 | 7-10 days | |
| 50 μg | $423 | 7-10 days | |
| 100 μg | $685 | 7-10 days | |
| 200 μg | $1,090 | 7-10 days | |
| 500 μg | $2,120 | 7-10 days | |
| 1 mg | $3,170 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q62312 |
| Synonyms | TβR-II,Transforming growth factor-β receptor type II,Transforming growth factor-beta receptor type II,TGF-β type II receptor,TGF-β receptor type-2,TGF-β receptor type II,TGFR-2,Tgfbr2,TGF-beta type II receptor,TGF-beta receptor type-2,TGF-beta receptor type II,TbetaR-II |
| Amino Acid | Ile24-Asp184 |
| Construction | Ile24-Asp184 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 60-75 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |

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