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Spesolimab (Synonyms: MAB92, BI 655130)

Catalog No. T76884 Copy Product Info
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Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.

Spesolimab

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Catalog No. T76884
Synonyms MAB92, BI 655130

Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.

Spesolimab
Cas No. 2097104-58-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$283In StockIn Stock
5 mg$742In StockIn Stock
10 mg$1,190-In Stock
25 mg$1,770-In Stock
50 mg$2,380-In Stock
100 mg$3,220-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
SynonymsMAB92, BI 655130
Reactivity
Human
Verified Activity
Immobilized Human IL-1RL2/IL-36R Protein (Fc) at 2 μg/mL (30 μL/well) can bind Spesolimab. The EC50 is 20.92 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-1RL2/IL-36R
Chemical Properties
Molecular Weight150 kDa
Cas No.2097104-58-8
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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