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Spesolimab

🥰Excellent
Catalog No. T76884Cas No. 2097104-58-8
Alias MAB92, BI 655130

Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.

Spesolimab

Spesolimab

🥰Excellent
Catalog No. T76884Alias MAB92, BI 655130Cas No. 2097104-58-8
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
Pack SizePriceAvailabilityQuantity
1 mg$283In Stock
5 mg$742In Stock
10 mg$1,190In Stock
25 mg$1,770In Stock
50 mg$2,380In Stock
100 mg$3,220In Stock
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Batch Information

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Concentration:4.09 mg/mL
Purity:> 95%
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Resource Download

COA SDS-PAGE SEC-HPLC Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity
Description
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
SynonymsMAB92, BI 655130
Chemical Properties
Molecular Weight150 kDa
Cas No.2097104-58-8
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SpesolimabILReceptorIL ReceptorIL receptorBI-655130BI655130
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