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Spesolimab
(Synonyms: MAB92, BI 655130) Copy Product Info
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Synonyms: MAB92, BI 655130
Catalog No. T76884 Copy Product Info
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Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
Cas No. 2097104-58-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $283 | In Stock | In Stock | |
| 5 mg | $742 | In Stock | In Stock | |
| 10 mg | $1,190 | - | In Stock | |
| 25 mg | $1,770 | - | In Stock | |
| 50 mg | $2,380 | - | In Stock | |
| 100 mg | $3,220 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1/Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | MAB92, BI 655130 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-1RL2/IL-36R Protein (Fc) at 2 μg/mL (30 μL/well) can bind Spesolimab. The EC50 is 20.92 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-1RL2/IL-36R |
| Molecular Weight | 150 kDa |
| Cas No. | 2097104-58-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Spesolimab chemical structure | Spesolimab molecular weight
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