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Anti-PRPF8 Antibody (4V102)
(Synonyms: U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p, U5 snRNP specific protein, Splicing factor Prp8, SNRNP220, RP13, Retinitis pigmentosa 13 (autosomal dominant), Prpf 8, PRPC8, PRP8_HUMAN, PRP8 pre mRNA processing factor 8 homolog, PRP8 homolog, PRP8, Pre-mRNA-processing-splicing factor 8, Precursor mRNA processing protein, Pre mRNA-processing factor 8, S. cerevisiae, homolog of, Pre mRNA processing factor 8, p220, HPRP8, Apoptosis regulated protein 2, Apoptosis regulated protein 1, 220 kDa U5 snRNP-specific protein, 220 kDa U5 snRNP specific protein) Copy Product Info
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Synonyms: U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p, U5 snRNP specific protein, Splicing factor Prp8, SNRNP220, RP13, Retinitis pigmentosa 13 (autosomal dominant), Prpf 8, PRPC8, PRP8_HUMAN, PRP8 pre mRNA processing factor 8 homolog, PRP8 homolog, PRP8, Pre-mRNA-processing-splicing factor 8, Precursor mRNA processing protein, Pre mRNA-processing factor 8, S. cerevisiae, homolog of, Pre mRNA processing factor 8, p220, HPRP8, Apoptosis regulated protein 2, Apoptosis regulated protein 1, 220 kDa U5 snRNP-specific protein, 220 kDa U5 snRNP specific protein
Catalog No. TMAC-03447 Copy Product Info
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Anti-PRPF8 Antibody (4V102) is a Rabbit antibody targeting PRPF8. Anti-PRPF8 Antibody (4V102) can be used in FCM,ICC,IHC,WB.
Anti-PRPF8 Antibody
(4V102)
(4V102)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-PRPF8 Antibody (4V102) is a Rabbit antibody targeting PRPF8. Anti-PRPF8 Antibody (4V102) can be used in FCM,ICC,IHC,WB. |
| Synonyms | U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p, U5 snRNP specific protein, Splicing factor Prp8, SNRNP220, RP13, Retinitis pigmentosa 13 (autosomal dominant), Prpf 8, PRPC8, PRP8_HUMAN, PRP8 pre mRNA processing factor 8 homolog, PRP8 homolog, PRP8, Pre-mRNA-processing-splicing factor 8, Precursor mRNA processing protein, Pre mRNA-processing factor 8, S. cerevisiae, homolog of, Pre mRNA processing factor 8, p220, HPRP8, Apoptosis regulated protein 2, Apoptosis regulated protein 1, 220 kDa U5 snRNP-specific protein, 220 kDa U5 snRNP specific protein |
| Ig Type | IgG |
| Clone | 4V102 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | PRP8, also designated pre-mRNA-processing-splicing factor 8, is a highly conserved nuclear protein and a central component of the catalytic core of the spliceosome, where it may be involved in various molecular rearrangements. PRP8, which is widely expressed, plays a role in transesterification reactions that regulate splicesome-induced pre-mRNA splicing. Specifically, PRP8 interacts with the GU dinucleotide at the 5' splice site (5'SS) and forms a specific UV-inducible cross-link. It also interacts functionally with the 3'SS, affecting the efficiency of the second catalytic step. PRP8 may play a role in the first transesterification step, as PRP8 mutations that prohibit negative regulation of PRP28 or PRP44/Brr2 subsequently block U4 activation. In addition, PRP8 interacts with a conserved region of U6 that is instrumental in the formation of the catalytic core of the spliceosome. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: 1C200 of human PRPF8 |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Theoretical: 274 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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