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Phosphatidylserine
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Catalog No. T35577Cas No. 1446756-47-3
Alias Serine glycerophosphatides, Phospholipids, phosphatidylserines
Phosphatidylserine is a phospholipid naturally present in mammals, exhibiting anti-inflammatory and anti-atherosclerotic effects. It activates PKC, neutral sphingolipidase, C-raf-1 protein kinase, and other cofactors involved in multiple signaling pathway activations.
Phosphatidylserine
Phosphatidylserine
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Catalog No. T35577Alias Serine glycerophosphatides, Phospholipids, phosphatidylserinesCas No. 1446756-47-3
Phosphatidylserine is a phospholipid naturally present in mammals, exhibiting anti-inflammatory and anti-atherosclerotic effects. It activates PKC, neutral sphingolipidase, C-raf-1 protein kinase, and other cofactors involved in multiple signaling pathway activations.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 mg | $1,180 | 35 days | 35 days | |
| 100 mg | $2,170 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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Product Introduction
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Storage & Solubility Information
| Description | Phosphatidylserine is a phospholipid naturally present in mammals, exhibiting anti-inflammatory and anti-atherosclerotic effects. It activates PKC, neutral sphingolipidase, C-raf-1 protein kinase, and other cofactors involved in multiple signaling pathway activations. |
| In vitro | Phosphatidylserine suppresses inflammation in tissues by inducing TGF-β secretion, thereby avoiding immune response activation through regulatory T cell production [4]. MS049 (0.1–10 μM; 20 h) concentration-dependently reduced H3R2me2a labeling in HEK293 cells [1]. |
| In vivo | Phosphatidylserine (0.5 mg liposome; single dose; subcutaneous injection) forms liposomes with PC and cholesterol in a 30:30:40 molar ratio. These liposomes suppress in vivo immune responses by binding to and enhancing activation of phosphatidylserine receptors [4]. |
| Synonyms | Serine glycerophosphatides, Phospholipids, phosphatidylserines |
| Molecular Weight | 788.1 |
| Formula | C42H78NO10P (for oleoyl) |
| Cas No. | 1446756-47-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Chloroform: Soluble, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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