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Anti-PCSK9 Antibody (4A946)
😃Good
Catalog No. TMAY-03673
Alias proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Anti-PCSK9 Antibody (4A946) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (4A946) can be used in ELISA(Cap).
Anti-PCSK9 Antibody (4A946)
Anti-PCSK9 Antibody (4A946)
😃Good
Catalog No. TMAY-03673Alias proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3
Anti-PCSK9 Antibody (4A946) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (4A946) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $68 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PCSK9 Antibody (4A946) is a Mouse antibody targeting PCSK9. Anti-PCSK9 Antibody (4A946) can be used in ELISA(Cap). |
| Alias | proprotein convertase subtilisin/kexin type 9, PC9, NARC-1, NARC1, LDLCQ1, HCHOLA3, FH3 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4A946 |
| Reactivity | Rat |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat PCSK9 / NARC1 (rR PCSK9 / NARC1; TMPY-01565; NP_954862.2; Met1-Gln691). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 protein is an enzyme which in humans is encoded by the PCSK9 gene with orthologs found across many species. It is expressed in neuroepithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells. PCSK9 protein is highly expressed in the liver and regulates low density lipoprotein receptor (LDLR) protein levels. Inhibition of PCSK9 protein function is currently being explored as a means of lowering cholesterol levels. Thereby, PCSK9 protein is regarded as a new strategy to treat hypercholesterolemia. PCSK9 protein contributes to cholesterol homeostasis and may have a role in the differentiation of cortical neurons. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Rat PCSK9 / NARC1 Protein (TMPY-01565) |
| Antigen Species | Rat |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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