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Anti-Galectin-1 Antibody-HRP (5T956)
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Catalog No. TMAY-00566H
Alias lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1
Anti-Galectin-1 Antibody-HRP (5T956) is a HRP-conjugated Rabbit antibody targeting Galectin-1. Anti-Galectin-1 Antibody-HRP (5T956) can be used in ELISA.
Anti-Galectin-1 Antibody-HRP (5T956)
Anti-Galectin-1 Antibody-HRP (5T956)
😃Good
Catalog No. TMAY-00566HAlias lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1
Anti-Galectin-1 Antibody-HRP (5T956) is a HRP-conjugated Rabbit antibody targeting Galectin-1. Anti-Galectin-1 Antibody-HRP (5T956) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $409 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1 |
| Ig Type | Rabbit IgG |
| Clone | 5T956 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Galectin-1 (rh Galectin-1; TMPY-00976; NP_002296.1; Met1-Asp135), and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. This endogenous lectin widely expressed at sites of inflammation and tumor growth has been postulated as an attractive immunosuppressive agent to restore immune cell tolerance and homeostasis in autoimmune and inflammatory settings. On the other hand, galectin-1 contributes to different steps of tumor progression including cell adhesion, migration, and tumor-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. Evidence points to Gal-1 and its ligands as one of the master regulators of such immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation, and allergies as well as host-pathogen interactions. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human Galectin-1 protein (TMPY-00976) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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