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Votoplam HCl

🥰Excellent
Catalog No. T79865LCas No. 2407851-28-7
Alias Votoplam HCl(2407849-89-0 Free base), PTC-518 HCl, PTC518 HCl

Votoplam HCl (PTC-518 HCl) is the hydrochloride form of Votoplam.Votoplam is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which is primarily used to inhibit Huntington's disease (HD).

Votoplam HCl

Votoplam HCl

🥰Excellent
Purity: 99.49%
Catalog No. T79865LAlias Votoplam HCl(2407849-89-0 Free base), PTC-518 HCl, PTC518 HClCas No. 2407851-28-7
Votoplam HCl (PTC-518 HCl) is the hydrochloride form of Votoplam.Votoplam is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which is primarily used to inhibit Huntington's disease (HD).
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1 mg$296 In Stock
5 mg$727 In Stock
10 mg$987 In Stock
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Purity:99.49%
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Product Introduction

Bioactivity
Description
Votoplam HCl (PTC-518 HCl) is the hydrochloride form of Votoplam.Votoplam is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which is primarily used to inhibit Huntington's disease (HD).
AliasVotoplam HCl(2407849-89-0 Free base), PTC-518 HCl, PTC518 HCl
Chemical Properties
Molecular Weight455.94
FormulaC21H26ClN9O
Cas No.2407851-28-7
SmilesCl.OC=1C=C(C=CC1C2=NN=C3C(N=NN3C4CC(NC(C)(C)C4)(C)C)=C2)N5N=CC=N5
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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