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Anti-GSTM2 Antibody (6I325) is a Rabbit antibody targeting GSTM2. Anti-GSTM2 Antibody (6I325) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-GSTM2 Antibody (6I325) is a Rabbit antibody targeting GSTM2. Anti-GSTM2 Antibody (6I325) can be used in IHC-P. |
Alias | GTHMUS, GSTM2-2, GSTM, GST4, glutathione S-transferase mu 2 (muscle) |
Ig Type | Monoclonal Rabbit IgG |
Clone | 6I325 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human GSTM2 in human leiomyoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human GSTM2 in human heart with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human GSTM2 in human epididymis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).Positive staining was localized to skeletal muscle. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human GSTM2 (rh GSTM2; TMPY-02223; P28161; Met1-Lys218). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. Butyrate, an important luminal component produced from the fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotective by increasing detoxification capabilities in the colon mucosa. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human GSTM2 protein (TMPY-02223) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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