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MAPK13-IN-1

Name: MAPK13-IN-1
Brand: TargetMol
SKU: T11943
Price: 100 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11943Cas No. 229002-10-2

MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).

MAPK13-IN-1

🥰Excellent

Purity: 99.62%

Catalog No. T11943Cas No. 229002-10-2

MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).

Pack Size	Price	Availability
1 mg	$100	In Stock
2 mg	$147	In Stock
5 mg	$247	In Stock
10 mg	$372	In Stock
25 mg	$643	In Stock
50 mg	$932	In Stock
100 mg	$1,360	In Stock
500 mg	$2,720	In Stock
1 mL x 10 mM (in DMSO)	$272	In Stock

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Batch Information

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Purity:99.62%

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
Targets&IC50	MAPK13 p38δ:620 nM

Chemical Properties

Molecular Weight	365.43
Formula	C₂₀H₂₃N₅O₂
Cas No.	229002-10-2
Smiles	Cn1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2)cc1)C(C)(C)C
Relative Density.	1.20 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 73.09 mg/mL (200.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7365 mL	13.6825 mL	27.3650 mL	136.8251 mL
5 mM	0.5473 mL	2.7365 mL	5.4730 mL	27.3650 mL
10 mM	0.2737 mL	1.3683 mL	2.7365 mL	13.6825 mL
20 mM	0.1368 mL	0.6841 mL	1.3683 mL	6.8413 mL
50 mM	0.0547 mL	0.2737 mL	0.5473 mL	2.7365 mL
100 mM	0.0274 mL	0.1368 mL	0.2737 mL	1.3683 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc