IGF1/IGF-I Protein, Mouse, Recombinant

Name: IGF1/IGF-I Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPY-04878
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: insulin-like growth factor 1 (somatomedin C), Igf-I, Igf-1, C730016P09Rik) Copy Product Info

Synonyms: insulin-like growth factor 1 (somatomedin C), Igf-I, Igf-1, C730016P09Rik

Catalog No. TMPY-04878 Copy Product Info

Purity: 97.7%

IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.

Pack Size	Price	USA Stock	Global Stock
5 µg	$45	-	In Stock
10 µg	$68	-	In Stock
20 µg	$108	-	In Stock
50 µg	$212	-	In Stock
100 µg	$358	7-10 days	7-10 days
200 µg	$615	7-10 days	7-10 days
500 µg	$1,250	7-10 days	7-10 days
1 mg	$2,170	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:97.7%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 0.2-1.2 μg/mL.
Description	IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
Species	Mouse
Expression System	P. pastoris (Yeast)
Tag	Tag Free
Accession Number	E9PU89
Construction	A DNA sequence encoding the mouse IGF1 (NP_001104744.1) (Gly49-Ala118) was expressed. Predicted N terminal: Gly 49
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	insulin-like growth factor 1 (somatomedin C), Igf-I, Igf-1, C730016P09Rik
Research Background	IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ), and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also about enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness, and mental retardation.

Chemical Properties

Molecular Weight

7.7 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.