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Anti-TNF-alpha Antibody (3M493)

Catalog No. TMAY-03656 Copy Product Info
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Anti-TNF-alpha Antibody (3M493) is a Mouse antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (3M493) can be used in ELISA.

Anti-TNF-alpha Antibody (3M493)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03656

Anti-TNF-alpha Antibody (3M493) is a Mouse antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (3M493) can be used in ELISA.

Anti-TNF-alpha Antibody
(3M493)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TNF-alpha Antibody (3M493) is a Mouse antibody targeting TNF-alpha. Anti-TNF-alpha Antibody (3M493) can be used in ELISA.
Ig Type
Mouse IgG1
Clone
3M493
Reactivity
Canine
Specificity
Canine TNF-alpha
No cross-reactivity in ELISA with
Human TNF-α
Mouse TNF-α
Rat TNF-α
E.coli cell lysate
Application
Recommended Dose
ELISA: 0.5-1 μg/mL
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Canine TNF-alpha (rCanine TNF-alpha; Catalog #70003-DNAE; NP_001003244.4; Val 77-Leu 233). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 5% trehalose
Research BackgroundTumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Canine TNF-alpha Protein (TMPY-01594)
Antigen Species
Canine
Biology Area
Cancer Drug Targets, Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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