Anti-Parkinson's Disease Compound Library

Catalog No. L9830

Library Compound List Excel SDF

Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by an extensive and progressive loss of dopaminergic neurons in the substantia nigra pars compacta. The incidence of PD is 1 percent of the population over the age of 60. This increases to 5 percent of the population over age 85. This makes aging is the biggest risk factor for developing PD. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. PD also had more severe insomnia and more symptoms of depression. The cause of PD is not known, but a number of genetic risk factors have now been characterized, as well as several genes which cause rare familial forms of PD. Environmental influences such as smoking, caffeine consumption, and pesticide exposure have been postulated to alter the risk of PD development, although the role of these remains unclear. PD is a multifactorial disease, with both genetic and environmental factors playing a role. Currently PD cannot be cured. Treatment predominantly focuses on symptomatic relief with drugs aiming to either restore the level of dopamine in the striatum or to act on striatal post-synaptic dopamine receptors, but none has yet been shown to slow the progression of the disease in humans.

Available drugs for PD include Levodopa, monoamine oxidase inhibitors (MAOIs), dopamine agonists, Glutamate antagonist, the putative N-meihyl-o-aspartaie (NMDA) receptor antagonists, COMT inhibitors, Anticholinergics, and the muscarinic receptor blockers, etc.

TargetMol’s Anti-Parkinson's Disease Compound Library, containing 908 compounds with anti-PD activities or acting on main drug targets of PD, can be used for related drug discovery and pharmacology research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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Product Description

A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
Targets include Dopamine Receptor, COMT, MAO-B, 5-HT Receptor, etc.
Some of them are FDA approved.
Structurally diverse, medicinally active, and cell permeable;
Detailed information about compound structure, target, activity, IC50, etc.
NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Library Composition

5-HT Receptor (237)

Dopamine Receptor (152)

AChR (122)

GABA Receptor (93)

Opioid Receptor (64)

NMDAR (44)

Adrenergic Receptor (40)

Histamine Receptor (39)

GluR (27)

Norepinephrine (21)

LRRK2 (18)

MAO (17)

Adenosine Receptor (13)

Calcium Channel (11)

Potassium Channel (10)

P450 (9)

Bcr-Abl (9)

Sodium Channel (8)

ROS (8)

Transferase (6)

Apoptosis (6)

Endogenous Metabolite (6)

Dehydrogenase (5)

BCL (4)

Aurora Kinase (4)

COX (4)

Mitochondrial Metabolism (4)

Autophagy (4)

Histone Methyltransferase (3)

PI3K (3)

PARP (3)

IκB/IKK (3)

FLT (3)

NOS (3)

Sigma receptor (3)

NF-κB (3)

Chloride channel (3)

Src (3)

TNF (3)

Caspase (3)

Antifection (2)

Antifungal (2)

Beta Amyloid (2)

JNK (2)

JAK (2)

Antibacterial (2)

CaMK (2)

IL Receptor (2)

p53 (2)

Parasite (2)

Carbonic Anhydrase (2)

PDE (2)

MMP (2)

EGFR (2)

CDK (2)

c-Kit (2)

Estrogen/progestogen Receptor (2)

Serotonin Transporter (2)

HDAC (2)

RAAS (1)

SGLT (1)

Vitamin (1)

Tyrosinase (1)

NOD (1)

TRP/TRPV Channel (1)

Trk receptor (1)

Na-K-Cl cotransporter (1)

Syk (1)

RAR/RXR (1)

TGF-beta/Smad (1)

Prostaglandin Receptor (1)

S6 Kinase (1)

Rho (1)

Transaminase (1)

P2 Receptor (1)

transporter (1)

Reactive Oxygen Species (1)

Phospholipase (1)

Hydroxylase (1)

mTOR (1)

DNA/RNA Synthesis (1)

Glucocorticoid Receptor (1)

GluCls (1)

Gamma-secretase (1)

FGFR (1)

FAAH (1)

Epigenetic Reader Domain (1)

DYRK (1)

DNA Alkylation (1)

GPR (1)

Decarboxylase (1)

c-Met/HGFR (1)

CCR (1)

Cannabinoid Receptor (1)

Annexin A (1)

Androgen Receptor (1)

Amino Acids and Derivatives (1)

AChE (1)

Glucokinase (1)

GRK (1)

MRP (1)

iGluR (1)

Monoamine Transporter (1)

MLK (1)

Microtubule Associated (1)

MEK (1)

Mdm2 (1)

MAPK (1)

Lipoxygenase (1)

IGF-1R (1)

GST (1)

IAP (1)

ABC (1)

HSP (1)

HMG-CoA Reductase (1)

HIV Protease (1)

Histone Demethylase (1)

HER (1)

HCV Protease (1)

Wnt/beta-catenin (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty