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TargetMol | Compound Library

Anti-Parkinson's Disease Compound Library

Catalog No. L9830

Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by an extensive and progressive loss of dopaminergic neurons in the substantia nigra pars compacta. The incidence of PD is 1 percent of the population over the age of 60. This increases to 5 percent of the population over age 85. This makes aging is the biggest risk factor for developing PD. Parkinson's disease symptoms include muscle rigidity, tremors, and changes in speech and gait. PD also had more severe insomnia and more symptoms of depression. The cause of PD is not known, but a number of genetic risk factors have now been characterized, as well as several genes which cause rare familial forms of PD. Environmental influences such as smoking, caffeine consumption, and pesticide exposure have been postulated to alter the risk of PD development, although the role of these remains unclear. PD is a multifactorial disease, with both genetic and environmental factors playing a role. Currently PD cannot be cured. Treatment predominantly focuses on symptomatic relief with drugs aiming to either restore the level of dopamine in the striatum or to act on striatal post-synaptic dopamine receptors, but none has yet been shown to slow the progression of the disease in humans. Available drugs for PD include Levodopa, monoamine oxidase inhibitors (MAOIs), dopamine agonists, Glutamate antagonist, the putative N-meihyl-o-aspartaie (NMDA) receptor antagonists, COMT inhibitors, Anticholinergics, and the muscarinic receptor blockers, etc.  TargetMol's Anti-Parkinson's Disease Compound Library, containing 857 compounds with anti-PD activities or acting on main drug targets of PD, can be used for related drug discovery and pharmacology research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9830

Anti-Parkinson's Disease Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
  • Targets include Dopamine Receptor, COMT, MAO-B, 5-HT Receptor, etc.
  • Some of them are FDA approved.
  • Structurally diverse, medicinally active, and cell permeable;
  • Detailed information about compound structure, target, activity, IC50, etc.
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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5-HT Receptor
Dopamine Receptor
AChR
GABA Receptor
Opioid Receptor
Histamine Receptor
Adrenergic Receptor
Apoptosis
Autophagy
NMDAR
iGluR
Endogenous Metabolite
GluR
Reactive Oxygen Species
TRP/TRPV Channel
Serotonin Transporter
Norepinephrine
MAO
LRRK2
Adenosine Receptor
Potassium Channel
Antibacterial
Calcium Channel
Sodium Channel
Cytochromes P450
Monoamine Oxidase
Transferase
Bcr-Abl
Cholinesterase (ChE)
Influenza Virus
Mitochondrial Metabolism
Parasite
NF-κB
Antifungal
Beta Amyloid
COX
Dehydrogenase
Ferroptosis
HIV Protease
Mitophagy
ROS
Src
Aurora Kinase
Bcl-2 Family
CaMK
Caspase
FLT
Histone Methyltransferase
NO Synthase
PDE
Sigma receptor
Antibiotic
Drug Metabolite
Gamma-secretase
HCV Protease
HER
IL Receptor
IκB/IKK
JAK
NOS
PARP
P-gp
PI3K
PPAR
TNF
Trk receptor
Virus Protease
Anti-infection
Cannabinoid Receptor
Carbonic Anhydrase
CDK
Chloride channel
c-Kit
DNA/RNA Synthesis
Estrogen/progestogen Receptor
FGFR
HDAC
JNK
MMP
Monoamine Transporter
p53
Phospholipase
Prostaglandin Receptor
RAAS
transporter
ABC Transporter
Acyltransferase
Amino Acids and Derivatives
Androgen Receptor
Annexin A
Arrestin
Aryl Hydrocarbon Receptor
CCR
c-Met/HGFR
CRISPR/Cas9
Decarboxylase
DNA Alkylation
DUB
DYRK
E1/E2/E3 Enzyme
Epigenetic Reader Domain
FAAH
GluCls
Glucocorticoid Receptor
Glucosidase
GPR
GRK
GST
HBV
Hexokinase
Histone Demethylase
HMG-CoA Reductase
HSP
HSV
Hydroxylase
IAP
IFNAR
IGF-1R
Imidazoline Receptor
Interleukin
Lipoxygenase
MAPK
MEK
Melatonin Receptor
Microtubule Associated
MLK
MRP
mTOR
Na+/Ca2+ Exchanger
NADPH
Neprilysin
NOD
NOD-like Receptor (NLR)
Nrf2
OAT
P2X Receptor
p38 MAPK
PKA
Progesterone Receptor
RAR/RXR
Ras
Retinoid Receptor
Rho
ROCK
ROR
RSV
S6 Kinase
SGK
SGLT
STAT
Stearoyl-CoA Desaturase (SCD)
STING
Syk
TGF-beta/Smad
Transaminase
Tyrosinase
VEGFR
Wnt/beta-catenin

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