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Synonyms: interleukin 1 receptor antagonist

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $87 | 7-10 days | 7-10 days | |
| 10 μg | $142 | 7-10 days | 7-10 days | |
| 20 μg | $233 | 7-10 days | 7-10 days | |
| 50 μg | $535 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized rat IL1R1-His at 10 μg/ml (100 μl/well) can bind rat Fc-IL1RN, The EC50 of rat Fc-IL1RN is 5.1-11.9 ng/ml. |
| Description | IL-1RA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is P25086. |
| Species | Rat |
| Expression System | HEK293 Cells |
| Tag | N-hFc |
| Accession Number | P25086 |
| Construction | A DNA sequence encoding the rat IL1RN (P25086) (His27-Gln178) was expressed, fused with Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu |
| Protein Purity | > 85 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | interleukin 1 receptor antagonist |
| Research Background |
| Molecular Weight | 45.8 kDa (predicted); 47 kDa (reducing condition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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