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Phage-derived 12/1 peptide
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Catalog No. TP2615Cas No. 186180-20-1
Phage-derived 12/1 peptide demonstrates antitumor activity by targeting MDM2 and MDMX, thereby disrupting the MDM2-p53 and MDMX-p53 interactions, with IC50 values of 0.15 and 1.25 μM, respectively [1].
Phage-derived 12/1 peptide
😃Good
Catalog No. TP2615Cas No. 186180-20-1
Phage-derived 12/1 peptide demonstrates antitumor activity by targeting MDM2 and MDMX, thereby disrupting the MDM2-p53 and MDMX-p53 interactions, with IC50 values of 0.15 and 1.25 μM, respectively [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Phage-derived 12/1 peptide demonstrates antitumor activity by targeting MDM2 and MDMX, thereby disrupting the MDM2-p53 and MDMX-p53 interactions, with IC50 values of 0.15 and 1.25 μM, respectively [1]. |
| Molecular Weight | 1558.78 |
| Formula | C71H99N17O19S2 |
| Cas No. | 186180-20-1 |
| Sequence | Met-Pro-Arg-Phe-Met-Asp-Tyr-Trp-Glu-Gly-Leu-Asn |
| Sequence Short | MPRFMDYWEGLN |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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